Mach-1Mechanical Testing System - Scientific Publications & Material


Pitney, M., van Niekerk, E., Dokos, S., Pelletier, M., & Walsh, W. R. (2013). Longitudinal Stent Deformation: Importance of Stent Type and Stent Apposition. American Journal of Biomedical Engineering, 3(3), 63-69. Full Text

Coutu, J.-M. (2012). Influence de l'agent de contraste sur les propriétés du thermogel de chitosane vers un nouvel agent embolisant pour les anévrismes. (Maîtrise), École de technologie supérieure. Abstract

Suen, R. S., Rampersad, S. N., Stewart, D. J., & Courtman, D. W. (2011). Differential roles of endothelin-1 in angiotensin II-induced atherosclerosis and aortic aneurysms in apolipoprotein E-null mice. The American journal of pathology, 179(3), 1549-1559. Abstract

Arribas, S. M., Briones, A. M., Bellingham, C., González, M. C., Salaices, M., Liu, K., Wang, Y., Hinek, A. (2008). Heightened aberrant deposition of hard-wearing elastin in conduit arteries of prehypertensive SHR is associated with increased stiffness and inward remodeling. Am J Physiol Heart Circ Physiol, 295(6), H2299-2307. Abstract

Iliopoulos, J. (2006). The Aortic Wrap Procedure: A Surgical Method of Treating Age-Related Aortic Dilatation and Stiffness. (PhD), University of New South Wales, Sydney.

Articular Cartilage

S. Sim, A. Chevrier, M. Garon, E. Quenneville and Michael D. Buschmann. Novel Technique to Map the Biomechanical Properties of Entire Articular Surfaces Using Indentation to Identify Early Osteoarthritis-like Regions. Podium presentation ID: 18-5. Annual conference of the European Society for Biomaterials, August 31 - September 3, 2014, Liverpool, UK. Presentation

S. Sim, A. Chevrier, M. Garon, E. Quenneville, and M.D. Buschmann (2014) Indentation Method to Map Mechanical Properties of Articular Surface to Identify Degenerated Regions. Podium presentation ID: OP-Sat-3-4. Annual Meeting of the Biomedical Engineering Society, October 22-25, 2014, San Antonio, TX, USA. Presentation

J.-F. Lavoie, S. Sim, A. Moreau, C.-É. Aubin, E. Quenneville, M. Garon, and M.D. Bushmann (2014) Mapping Biomechanical Properties of Mice Articular Surfaces Using Indentation: Preliminary Results. Poster ID: P-Th-183. Poster

S. Sim, A. Chevrier, M. Garon, E. Quenneville, and M.D. Buschmann (2014) Novel Technique to Map the Biomechanical Properties of Entire Articular Surfaces Using Indentation to Identify Degenerated (Osteoarthritis-like) Cartilage. Poster 2229. World Congress on Biomechanics, July 6-11, 2014, Boston, MA, USA. Poster

S. Sim, A. Chevrier, M. Garon, E. Quenneville, and M.D. Buschmann (2014) Novel Technique to Map the Biomechanical Properties of Entire Articular Surfaces Using Indentation to Identify Early Osteoarthritis-like Regions. Podium presentation ID:O7.05. International Conference on BioTribology, May 11-14, 2014, Toronto, Canada. Presentation

Qin, J., Chow, S. K.-H., Guo, A., Wong, W.-N., Leung, K.-S., & Cheung, W.-H. (2014) Low Magnitude High Frequency Vibration Accelerated Cartilage Degeneration but Improved Epiphyseal Bone Formation in Anterior Cruciate Ligament Transect Induced Osteoarthritis Rat Model. Osteoarthritis and Cartilage. Abstract

Sim, S., Lavoie, J. F., Moreau, A., Quenneville, E., Garon, M., & Buschmann, M. D. (2014) Novel Technique to Map the Biomechanical Properties of Entire Mice Articular Surfaces Using Indentation. Osteoarthritis and Cartilage, 22(1), 541. World Congress on Osteoarthritis, April 2014, Paris, France. Poster

S. Sim, A. Chevrier, M. Garon, E. Quenneville and M.D. Buschmann. Novel Technique to Map the Biomechanical Properties of Entire Articular Surfaces Using Indentation to Identify Osteoarthritis-like Regions. Paper presented at the Transactions of the 60th Annual Meeting of the Orthopaedic Research Society, New Orleans, LA, USA, 2015. Poster

Sim, S., Quenneville, E., Garon, M., Hoemann, C. D., Hurtig, M., & Buschmann, M. D. (2013) Evaluation of a novel technique to map the mechanical properties of an entire articular surface in indentation. Paper presented at the Transactions International Cartilage Repair Society, 11.2.9, Izmir, Turkey. Presentation

Chan, E. F., Liu, I.-L., Semler, E. J., Aberman, H. M., Simon, T. M., Chen, A. C., Truncale, K.G., Sah, R. L. (2012) Association of 3-dimensional cartilage and bone structure with articular cartilage properties in and adjacent to autologous osteochondral grafts after 6 and 12 months in a goat model. Cartilage, 3(3), 255-266. Abstract

Seifzadeh, A., Oguamanam, D., Trutiak, N., Hurtig, M., & Papini, M. (2012). Determination of nonlinear fibre-reinforced biphasic poroviscoelastic constitutive parameters of articular cartilage using stress relaxation indentation testing and an optimizing finite element analysis. Computer methods and programs in biomedicine, 107(2), 315-326. Abstract

Report following the ICRS Laboratory Skills Course in Translational Science in Montreal (Quebec, Canada), from May 31 to June 3, 2011. Report

Changoor, A., Garon, M., Hurtig, M., Buschmann, M., Quenneville, E., & Coutu, J. (2011). Streaming potential-based arthroscopic device is sensitive to cartilage changes immediately post-impact in an equine cartilage injury model. Journal of biomechanical engineering, 133(6), 061005. Abstract

Changoor, A., Yaroshinsky, A., Buschmann, M. D., & Fereydoonzad, L. (2010). Effects of refrigeration and freezing on the electromechanical and biomechanical properties of articular cartilage. Journal of biomechanical engineering, 132(6), 064502. Abstract

Hwang, J., Kyubwa, E. M., Bae, W. C., Bugbee, W. D., Masuda, K., & Sah, R. L. (2010). In Vitro Calcification of Immature Bovine Articular Cartilage Formation of a Functional Zone of Calcified Cartilage. Cartilage, 1(4), 287-297. doi: 10.1177/1947603510369552 Abstract

Lane, J., Healey, R., Chen, A., Sah, R., & Amiel, D. (2010). Can osteochondral grafting be augmented with microfracture in an extended-size lesion of articular cartilage? . Am J Sports Med. 2010 Jul, 38(7), 1316-1323. Abstract

Nguyen, Q. T., Wong, B. L., Chun, J., Yoon, Y. C., Talke, F. E., & Sah, R. L. (2010). Macroscopic assessment of cartilage shear: Effects of counter-surface roughness, synovial fluid lubricant, and compression offset. Journal of biomechanics, 43(9), 1787-1793. Abstract

Wong, B. L., Bae, W. C., Chun, J., Gratz, K. R., Lotz, M., & Sah, R. L. (2008). Biomechanics of cartilage articulation: effects of lubrication and degeneration on shear deformation. Arthritis & Rheumatism, 58(7), 2065-2074. Abstract

Bae, W., Schumacher, B., & Sah, R. (2007). Indentation probing of human articular cartilage: effect on chondrocyte viability. Osteoarthritis and Cartilage, 15(1), 9-18. Abstract

Horstman, C., McLaughlin, R., Elder, S., Pool, R., Read, R., & Boyle, C. (2006). Biomechanical and metabolic changes within rabbit articular cartilage following treatment with radiofrequency energy. Paper presented at the Podium presentation at the 2nd Annual World Veterinary Orthopaedic Congress, Keystone, CO, USA.

Kandel, R., Grynpas, M., Pilliar, R., Lee, J., Wang, J., Waldman, S., Zalzal, P., Hurtig, M. (2006). Repair of osteochondral defects with biphasic cartilage-calcium polyphosphate constructs in a sheep model. Biomaterials, 27(22), 4120-4131. Abstract

Nugent, G. E. (2006). Biomechanical regulation of articular cartilage metabolism of proteoglycan 4 and articular surface integrity. (PhD), University of California, San Diego, USA. Full text

Nugent, G. E., Aneloski, N. M., Schmidt, T. A., Schumacher, B. L., Voegtline, M. S., & Sah, R. L. (2006). Dynamic shear stimulation of bovine cartilage biosynthesis of proteoglycan 4. Arthritis & Rheumatism, 54(6), 1888-1896. Abstract

Valverde-Franco, G., Binette, J. S., Li, W., Wang, H., Chai, S., Laflamme, F., Tran-Khanh, N., Quenneville, E., Meijers, T., Poole, A. R., Mort, J. S., Buschmann, M. D. and Henderson, J. E. (2006) Defects in articular cartilage metabolism and early arthritis in fibroblast growth factor receptor 3 deficient mice. Human molecular genetics, 15(11), 1783-1792. Abstract

Binette, J.S., Laflamme, F., Li, W., Valverde-Franco, G., Tran-Khanh, N., Quenneville, E., Henderson, J.E., and Buschmann, M.D. (2005) Novel Biomechanical Indentation Test Demonstrates Joint Surface Weakening in Mice Lacking Fibroblast Growth Factor Receptor 3 (FGFR3). Paper presented at the 11th Canadian Connective Tissue Conference, Montreal, QC, Canada. Poster

Bae, W., Law, A., Amiel, D., & Sah, R. (2004). Sensitivity of indentation testing to step-off edges and interface integrity in cartilage repair. Ann Biomed Eng, 32(3), 360-369. Abstract

Charlebois, M., McKee, M. D., & Buschmann, M. D. (2004). Nonlinear Tensile Properties of Bovine Articular Cartilage and Their Variation With Age and Depth. Journal of biomechanical engineering, 26, 129-137. Abstract

Nugent, G.E., Law, A.W., Wong, E.G., Temple, M.M., Bae, W.C., Chen, A.C., Kawcak, C.E., Sah, R.L. (2004) Site- and exercise-related variation in structure and function of cartilage from equine distal metacarpal condyle. Osteoarthritis Cartilage, 12(10), 826-833. Abstract

Quenneville, E., Binette, J.-S., Garon, M., Légaré, A., Meunier, M., & Buschmann, M. D. (2004). Fabrication and characterization of nonplanar microelectrode array circuits for use in arthroscopic diagnosis of cartilage diseases. Biomedical Engineering, IEEE Transactions on, 51(12), 2164-2173. Abstract

Garon, M., Légaré, A., Quenneville, E., Hurtig, M., & Buschmann, M. (2003). Streaming potential based arthroscopic instrument distinguishes site-specific properties of equine articular cartilage. Paper presented to the Transactions of the 49th Annual Meeting of the Orthopaedic Research Society, New Orleans, LA, USA, 28:255. Slides | Abstract

Langelier, E., & Buschmann, M. D. (2003). Increasing strain and strain rate strengthen transient stiffness but weaken the response to subsequent compression for articular cartilage in unconfined compression. Journal of biomechanics, 36(6), 853-859. Abstract

Quenneville, E., Garon, M., Légaré, A., & Buschmann, M. (2003). Load and streaming potential responses of articular cartilage as a function of compression speed during indentation. Paper presented at the Proc. Orthopaedic Research Society Meeting. Abstract

Thibault, M., Poole, A., & Buschmann, M. D. (2002). Cyclic compression of cartilage/bone explants in vitro leads to physical weakening, mechanical breakdown of collagen and release of matrix fragments. Journal of orthopaedic research, 20(6), 1266-1274. Abstract

Fortin, M., Soulhat, J., Shirazi-Adl, A., Hunziker, E., & Buschmann, M. D. (2000). Unconfined Compression of Articular Cartilage : Nonlinear Behavior and Comparison with a Fibril-Reinforced Biphasic Model. Journal of biomechanical engineering, 122(2), 189-195. Abstract

Legare, A., Garon, M., Binette, F., & Buschmann, M. (2000). Evaluation of cartilage quality using streaming potential maps. Transact ICRS, 3, 89. Poster

Dumont, J., Ionescu, M., Reiner, A., Poole, A. R., Tran-Khanh, N., Hoemann, C. D., McKee, M.D., Buschmann, M. D. (1999). Mature full-thickness articular cartilage explants attached to bone are physiologically stable over long-term culture in serum-free media. Connective tissue research, 40(4), 259-272. Abstract

Quenneville, E., Garon, M., Légaré, A., & Buschmann, M. (1999). Positive electric potentials detected at the cartilage/bath interface during compression and their importance in clinical cartilage diagnostics. ASME J. Biomech. Eng, 121, 340-347. Poster

Soulhat, J., Buschmann, M. D., & Shirazi-Adl, A. (1999). A fibril-network-reinforced biphasic model of cartilage in unconfined compression. Journal of Biomechanical Engineering, Jun, 121(3), 340-347. Abstract


Viens, M., Chauvette, G., & Langelier, E. (2011). A Roadmap for the Design of Bioreactors in Mechanobiological Research and Engineering of Load-Bearing Tissues. Journal of Medical Devices, 5(4), 041006. doi: 10.1115/1.4005319 Abstract


Liang, L. D., Wagner, A., Steeds, J., Hurtig, M., & Gordon, K. (2013). Characterization of the effect of microfracture surgery and angle of incidence on the structural properties of femoral bone. Studies by Undergraduate Researchers at Guelph, 7(1), 56-61. Full text

Lovric, V., Chen, D., Yu, Y., Oliver, R. A., Genin, F., & Walsh, W. R. (2012). Effects of demineralized bone matrix on tendon-bone healing in an intra-articular rodent model. The American journal of sports medicine, 40(10), 2365-2374. Abstract

Henderson, J. E., Gao, C., & Harvey, E. J. (2011). Skeletal Phenotyping in Rodents: Tissue Isolation and Manipulation Osteoporosis Research (pp. 13-28). London: Springer. Abstract

Engbretson, A. C. (2010). Determining the modulus of intact bovine vertebral cancellous bone tissue: Development and validation of a protocol. (Master), Queen's University. Abstract

Valverde-Franco, G., Liu, H., Davidson, D., Chai, S., Valderrama-Carvajal, H., Goltzman, D., Ornitz, D. M. and Henderson, J. E. (2004) Defective Bone Mineralization and Osteopenia in Young Adult Fgfr3-/- Mice. Hum Mol Genet, 13(3), 271-284. Abstract

Gillies, R., Gan, J., O'Gorman, M., & Walsh, W. (2001). BM11: Using CT's to Measure Bone Remodeling Changes. Australasian Physical & Engineering Sciences in Medicine, 24(4), 271. Abstract

Central Nervous System

Begonia, M. G., Liao, J., Horstemeyer, M. F., & Williams, L. N. (2009). Strain Rate Dependence in the Structure Property Relationship of Porcine Brain. Paper presented at the ASME 2009 Summer Bioengineering Conference. Abstract

Solomon, J. H. (2008). A Biorobotic Study of the Rat Whisker System: ProQuest. Abstract

Elastic Fibres

Miao, M., Sitarz, E., Bellingham, C. M., Won, E., Muiznieks, L. D., & Keeley, F. W. (2013). Sequence and domain arrangements influence mechanical properties of elastin-like polymeric elastomers. Biopolymers, 99(6), 392-407. Abstract

He, D. (2012). The Sequence and Function Relationship of Elastin: How Repetitive Sequences can Influence the Physical Properties of Elastin. (Doctoral), University of Toronto. Abstract

He, D., Miao, M., Sitarz, E. E., Muiznieks, L. D., Reichheld, S., Stahl, R. J., Keeley, F. W., Parkinson, J. (2012). Polymorphisms in the Human Tropoelastin Gene Modify In Vitro Self-Assembly and Mechanical Properties of Elastin-Like Polypeptides. PloS one, 7(9), e46130. doi: 10.1371/journal.pone.0046130 Abstract

Vieth, S., Bellingham, C., Keeley, F., Hodge, S., & Rousseau, D. (2007). Microstructural and tensile properties of elastin-based polypeptides crosslinked with Genipin and pyrroloquinoline quinone. Biopolymers, 85(3), 199-206. Abstract

Fetal Membrane

Weed, B. C., Borazjani, A., Patnaik, S. S., Prabhu, R., Horstemeyer, M., Ryan, P. L., Franz, T., Williams, L.N., Liao, J. (2012). Stress State and Strain Rate Dependence of the Human Placenta. Annals of biomedical engineering, 40(10), 2255-2265. Abstract

Borazjani, A., Weed, B. C., Patnaik, S. S., Feugang, J. M., Christiansen, D., Elder, S. H., Ryan, P. L., Liao, J. (2011). A comparative biomechanical analysis of term fetal membranes in human and domestic species. American journal of obstetrics and gynecology, 204(4), 365. e325-365. e336. Abstract

Weed, B., Borazjani, A., Patnaik, S., Prabhu, R., Franz, T., Horstemeyer, M., Williams, L., Liao, J. (2011). Stress State Dependence of Human Placenta Mechanical Behavior. Paper presented at the ASME 2011 Summer Bioengineering Conference.

Growth Plate

Ménard, A.-L., Soulisse, C., Raymond, P., Londono, I., & Villemure, I. (2013). Effect of cold storage and freezing on the biomechanical properties of swine growth plate explants. Journal of biomechanical engineering. Abstract

Wosu, R., Sergerie, K., Lévesque, M., & Villemure, I. (2012). Mechanical properties of the porcine growth plate vary with developmental stage. Biomechanics and modeling in mechanobiology, 11(3-4), 303-312.

Sergerie, K., Parent, S., Beauchemin, P. F., Londoño, I., Moldovan, F., & Villemure, I. (2011). Growth plate explants respond differently to in vitro static and dynamic loadings. Journal of orthopaedic research, 29(4), 473-480. Abstract

Valteau, B., Grimard, G., Londono, I., Moldovan, F., & Villemure, I. (2011). In vivo dynamic bone growth modulation is less detrimental but as effective as static growth modulation. Bone, 49(5), 996-1004. Abstract

Valteau, B. P. (2011). Étude comparative in vivo de la compression statique et dynamique sur des vertèbres caudales de rat: effets sur le taux de croissance et sur l'histomorphométrie de la plaque de croissance. (Maîtrise), École Polytechnique de Montréal. Abstract

Sergerie, K., Gennaro, B., Eveno, A.-S., Dubois-Rioux, M.-C., Lacoursière, M.-O., & Villemure, I. (2009). Intrinsic Mechanical Properties of Porcine Growth Plates Vary With Developmental Stages. Paper presented at the Transactions of the 55th Annual Meeting of the Orthopaedic Research Society, Las Vegas, NV, USA

Sergerie, K., Lacoursière, M.-O., Lévesque, M., & Villemure, I. (2009). Mechanical Properties of the Porcine Growth Plate and its Three Zones From Unconfined Compression Tests. Journal of biomechanics, 42(4), 510-516. Abstract

Sergerie, K., Villemure, I., & Lacoursière, M.-O. (2008). Mechanical Properties of the Porcine Growth Plate and its Three Zones from Unconfined Compression Tests. Paper presented at the Transactions of the 54th Annual Meeting of the Orthopaedic Research Society, San Francisco, CA, USA.


Quist, B. W., Faruqi, R. A., & Hartmann, M. J. (2011). Variation in Young's modulus along the length of a rat vibrissa. Journal of biomechanics, 44(16), 2775-2781. Abstract

Birdwell, J. A., Solomon, J. H., Thajchayapong, M., Taylor, M. A., Cheely, M., Towal, R. B., Conradt, J., Hartmann, M. J. (2007). Biomechanical models for radial distance determination by the rat vibrissal system. Journal of neurophysiology, 98(4), 2439-2455. Abstract

Hand Soft Tissue

Wu, J. Z., Dong, R. G., Warren, C. M., Welcome, D. E., & McDowell, T. W. (2014). Analysis of the effects of surface stiffness on the contact interaction between a finger and a cylindrical handle using a three-dimensional hybrid model. Medical engineering & physics. Abstract

Wu, J. Z., Wimer, B. M., Welcome, D. E., & Dong, R. G. (2012). An analysis of contact stiffness between a finger and an object when wearing an air-cushioned glove: The effects of the air pressure. Medical engineering & physics, 34(3), 386-393. Abstract


Iliopoulos, J., Cornwall, G., Evans, R., Manganas, C., Thomas, K., Newman, D., & Walsh, W. (2004). Evaluation of a bioabsorable polylactide film in a large animal model for the reduction of retrosternal adhesions. Journal of Surgical Research, 118(2), 144-153. Abstract


Coutu, J. M., Fatimi, A., Berrahmoune, S., Soulez, G., & Lerouge, S. (2013). A new radiopaque embolizing agent for the treatment of endoleaks after endovascular repair: Influence of contrast agent on chitosan thermogel properties. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 101(1), 153-161. Abstract

Machado Roque, A. I. (2013). Protein scaffolds for cell culture. (PhD), Newcastle University. Abstract

Owen, S. C., Fisher, S. A., Tam, R. Y., Nimmo, C. M., & Shoichet, M. S. (2013). Hyaluronic acid click hydrogels emulate the extracellular matrix. Langmuir, 29(24), 7393-7400. Abstract

Snyders, R., Shingel, K. I., Zabeida, O., Roberge, C., Faure, M. P., Martinu, L., & Klemberg-Sapieha, J. E. (2007). Mechanical and microstructural properties of hybrid poly (ethylene glycol)-soy protein hydrogels for wound dressing applications. Journal of Biomedical Materials Research Part A, 83(1), 88-97. Abstract

Gauthier, M., Luo, J., Calvet, D., Ni, C., Zhu, X., Garon, M., & Buschmann, M. (2004). Degree of crosslinking and mechanical properties of crosslinked poly (vinyl alcohol) beads for use in solid-phase organic synthesis. Polymer, 45(24), 8201-8210. Abstract

Jarry, C., Chaput, C., Chenite, A., Renaud, M. A., Buschmann, M., & Leroux, J. C. (2001). Effects of steam sterilization on thermogelling chitosan-based gels. Journal of biomedical materials research, 58(1), 127-135. Abstract

Intervertebral Discs

Recuerda, M., Périé, D., Gilbert, G., & Beaudoin, G. (2012). Assessment of mechanical properties of isolated bovine intervertebral discs from multi-parametric magnetic resonance imaging. BMC musculoskeletal disorders, 13(1), 195. Abstract

Recuerda, M. (2010). Caractérisation des propriétés mécaniques des disques intervertébraux et de leurs relations avec l imagerie quantitative par résonance magnétique. (Maîtrise), École Polytechnique de Montréal. Abstract


Mammoto, A., Mammoto, T., Kanapathipillai, M., Yung, C. W., Jiang, E., Jiang, A., Lofgren, K., Gee, E. Ingber, D. E. (2013). Control of lung vascular permeability and endotoxin-induced pulmonary oedema by changes in extracellular matrix mechanics. Nature communications, 4, 1759. Abstract

Mammoto, T., Jiang, E., Jiang, A., & Mammoto, A. (2013). Extracellular Matrix Structure and Tissue Stiffness Control Postnatal Lung Development through the Lipoprotein Receptor-Related Protein 5/Tie2 Signaling System. American Journal of Respiratory Cell and Molecular Biology, 49(6), 1009-1018. Abstract

Hill, C. H., Ashwell, C. M., Nolin, S. J., Keeley, F., Billingham, C., Hinek, A., & Starcher, B. (2007). Dietary iron deficiency compromises normal development of elastic fibers in the aorta and lungs of chicks. The Journal of nutrition, 137(8), 1895-1900. Abstract

Pharmaceutical Tablets

Mulhbacher, J., Ispas-Szabo, P., Ouellet, M., Alex, S., & Mateescu, M. A. (2006). Mucoadhesive properties of cross-linked high amylose starch derivatives. International journal of biological macromolecules, 40(1), 9-14. Abstract

Ravenelle, F., Marchessault, R., Legare, A., & Buschmann, M. (2002). Mechanical properties and structure of swollen crosslinked high amylose starch tablets. Carbohydrate polymers, 47(3), 259-266. Abstract

Plantar Soft Tissue

Hayami, J. W., Waldman, S. D., & Amsden, B. G. (2013). Injectable, High Modulus, And Fatigue Resistant Composite Scaffold for Load-Bearing Soft Tissue Regeneration. Biomacromolecules, 14(12), 4236-4247. Abstract

Pai, S., Vawter, P. T., & Ledoux, W. R. (2013). The Effect of Prior Compression Tests on the Plantar Soft Tissue Compressive and Shear Properties. Journal of biomechanical engineering, 135(9), 094501.

Pai, S., & Ledoux, W. R. (2012). The shear mechanical properties of diabetic and non-diabetic plantar soft tissue. Journal of biomechanics, 45(2), 364-370. Summary, Abstract

Pai, S., Vawter, P., & Ledoux, W. (2012). The effect of prior compression tests on the plantar soft tissue compressive and shear elastic properties. Journal of Foot and Ankle Research 2012, 5(Suppl 1), 14. Abstract

Hayami, J. W., Waldman, S. D., & Amsden, B. G. (2011). A Photocurable Hydrogel/Elastomer Composite Scaffold with Bi-Continuous Morphology for Cell Encapsulation. Macromolecular bioscience, 11(12), 1672-1683. Abstract


Surrao, D. C., Hayami, J. W., Waldman, S. D., & Amsden, B. G. (2010). Self-crimping, biodegradable, electrospun polymer microfibers. Biomacromolecules, 11(12), 3624-3629. Abstract

Zhu, X., Zhang, J., Gauthier, M., Luo, J., Meng, F., & Brisse, F. (2006). Large Uniform-Sized Polymer Beads for Use as Solid-Phase Supports Prepared by Ascension Polymerization. Journal of combinatorial chemistry, 8(1), 79-84. Abstract

Baradie, B., & Shoichet, M. S. (2005). Novel fluoro-terpolymers for coatings applications. Macromolecules, 38(13), 5560-5568. Full Text

Griesser, H. J., McLean, K. M., Kingshott, P., Beumer, G. J., Thissen, H., Muir, B. W., & Hamilton-Brown, P. (2001). BM9: Bioactive'Hybrid'Polymeric Biomaterials. Australasian Physical & Engineering Sciences in Medicine, 24(4), 270. Abstract

Force Sensors

Sundara-Rajan, K., Bestick, A., Rowe, G., Klute, G., Ledoux, W., Wang, H., & Mamishev, A. (2012). An interfacial stress sensor for biomechanical applications. Measurement Science and Technology, 23(8), 085701. Abstract

Sundara-Rajan, K., Rowe, G. I., Bestick, A., Mamishev, A. V., Klute, G. K., & Ledoux, W. R. (2010). Capacitive sensing of interfacial forces in prosthesis. Paper presented at the Medical Measurements and Applications Proceedings (MeMeA), 2010 IEEE International Workshop on. Abstract


Wood, J., Soldin, M., Shaw, T. J., & Szarko, M. (2014). The biomechanical and histological sequelae of common skin banking methods. Journal of biomechanics. Abstract

Bowser, J., Elder, S., Pasquali, M., Grady, J., Rashmir-Raven, A., Wills, R., & Swiderski, C. (2013). Tensile properties in collagen-rich tissues of Quarter Horses with hereditary equine regional dermal asthenia (HERDA). Equine veterinary journal. Abstract

Lu, X., Sundara-Rajan, K., Lu, W., & Mamishev, A. V. (2013). Transfer Function of Interfacial Stress Sensor for Artificial Skin Applications. Electron Devices, IEEE Transactions on, 60(8), 2640-2647. Abstract

Grady, J. G., Elder, S. H., Ryan, P. L., Swiderski, C. E., & Rashmir-Raven, A. M. (2009). Biomechanical and molecular characteristics of hereditary equine regional dermal asthenia in Quarter Horses. Veterinary dermatology, 20(5-6), 591-599. Abstract

Wu, J., Cutlip, R., Andrew, M., & Dong, R. (2007). Simultaneous determination of the nonlinear-elastic properties of skin and subcutaneous tissue in unconfined compression tests. Skin Res Technol, 13(1), 34-42. Abstract

Authier, S., Fournier, S., Chaurand, F., Gordon, C., Garon, M., Cloutier, L., & Troncy, E. (November 2006). Validation of a surgical wound healing model in Sprague-Dawley rats. Paper presented at the 27th Annual Meeting of the American College of Toxicology. Poster

Wu, J., Cutlip, R., Welcome, D., & Dong, R. (2006). Estimation of the viscous properties of skin and subcutaneous tissue in uniaxial stress relaxation tests. Biomed Mater Eng. 2006, 16(1), 53-66. Abstract

Wu, J., Dong, R., Smutz, W., & Schopper, A. (2003). Nonlinear and viscoelastic characteristics of skin under compression: experiment and analysis. Biomed Mater Eng, 13(4), 373-385. Abstract

Stem Cells

Leipzig, N. D., Wylie, R. G., Kim, H., & Shoichet, M. S. (2011). Differentiation of neural stem cells in three-dimensional growth factor-immobilized chitosan hydrogel scaffolds. Biomaterials, 32(1), 57-64. Abstract

Leipzig, N. D., Xu, C., Zahir, T., & Shoichet, M. S. (2010). Functional immobilization of interferon-gamma induces neuronal differentiation of neural stem cells. Journal of Biomedical Materials Research Part A, 93(2), 625-633. Abstract

Suture Materials

Vizesi, F., Jones, C., Lotz, N., Gianoutsos, M., & Walsh, W. R. (2008). Stress relaxation and creep: viscoelastic properties of common suture materials used for flexor tendon repair. The Journal of hand surgery, 33(2), 241-246. Abstract

Acton, D., Perry, A., Evans, R., Butler, A., Stephens, P., Bruce, W., Goldberg, J., Sonnabend, D., Walsh, W. (2004). The effect of two nonresorbable suture types on the mechanical performance over a metal suture anchor eyelet. Knee Surgery, Sports Traumatology, Arthroscopy, 12(2), 165-168. Abstract


Jiménez Montenegro, V. C., Jones, A., Petocz, P., Gonzales, C., & Darendeliler, M. A. (2012). Physical properties of root cementum: Part 22. Root resorption after the application of light and heavy extrusive orthodontic forces: A microcomputed tomography study. American Journal of Orthodontics and Dentofacial Orthopedics, 141(1), e1-e9. Abstract

Phelan, A., Petocz, P., Walsh, W., Darendeliler, A., Soma, K. J., Thomson, W. M., Morgaine, K.C., Harding, W.J., Lim, E., Sameshima, G. (2012). The force-distance properties of attracting magnetic attachments for tooth movement in combination with clear sequential aligners. Australian orthodontic journal, 28(2), 159. Abstract

Tendons and Ligaments

Clemmer, J., Liao, J., Davis, D., Horstemeyer, M. F., & Williams, L. N. (2010). A mechanistic study for strain rate sensitivity of rabbit patellar tendon. Journal of biomechanics, 43(14), 2785-2791. Abstract

Scherman, P., Haddad, R., Scougall, P., & Walsh, W. R. (2010). Cross-sectional area and strength differences of fiberwire, prolene, and ticron sutures. The Journal of hand surgery, 35(5), 780-784. Abstract

Davis, D., Clemmer, J., Liao, J., Horsetemeyer, M. F., & Williams, L. N. (2009). Strain Rate Effects on Structure-Property Relationship in the Rabbit Patellar Tendon. Paper presented at the ASME 2009 Summer Bioengineering Conference. Abstract

Williams, L., Elder, S., Bouvard, J., & Horsetemeyer, M. (2008). The anisotropic compressive mechanical properties of the rabbit patellar tendon. Biorheology, 45(5), 577-586. Abstract

Schreuder, F., Scougall, P., Puchert, E., Vizesi, F., & Walsh, W. (2006). Effect of suture material on gap formation and failure in type 1 FDP avulsion repairs in a cadaver model. Clinical Biomechanics, 21(5), 481-484. Abstract

Latendresse, K., Dona, E., Scougall, P., Schreuder, F., Puchert, E., & Walsh, W. R. (2005). Cyclic testing of pullout sutures and micro-mitek suture anchors in flexor digitorum profundus tendon distal fixation. The Journal of hand surgery, 30(3), 471-478. Abstract

Matheson, G., Nicklin, S., Gianoutsous, M., & Walsh, W. (2005). Comparison of zone II flexor tendon repairs using an in vitro linear cyclic testing protocol. Clinical Biomechanics, 20(7), 718-722. Abstract

Butler, A. M., & Walsh, W. R. (2004). Mechanical response of ankle ligaments at low loads. Foot & ankle international, 25(1), 8-12. Abstract

Wu, J., Brumfield, A., Miller, G., Metheny, R., & Cutlip, R. (2004). Comparison of mechanical properties of rat tibialis anterior tendon evaluated using two different approaches. Biomed Mater Eng, 14(1), 13-22. Abstract

Diaz, R. Y., Gutierrez, V., Gonzalez, F. M., Dieguez, F. R., & Vergara, F. J. (2003). Paper# 84 Biologic dynamic patellar tendon repair. Arthroscopy: The Journal of Arthroscopic & Related Surgery, 19(6), 43. Abstract

Walsh, W., Svehla, M., & Gillies, R. (2002). Low Force Stress Relaxation of Ligament. Journal of Bone & Joint Surgery, British Volume, 84(SUPP III), 236-236. Abstract

Tissue Engineering - Annulus Fibrosus

Cho, H., Park, S. H., Park, K., Shim, J. W., Huang, J., Smith, R., Elder, S., Min, B. H., Hasty, K. A. (2013). Construction of a Tissue-Engineered Annulus Fibrosus. Artificial organs, 37(7), E131-E138. Abstract

Yeganegi, M. (2009). Characterization of a Biodegradable Electrospun Polyurethane Nanofiber Scaffold Suitable for Annulus Fibrosus Tissue Engineering. University of Toronto. Abstract

Kandel, R., & Santerre, J. P. (2008). Fibrous scaffold for use in soft tissue engineering. Google Patents. Full Text

Smith, L. J. (2008). Structure and Function of the Elastic Fibre Network of the Human Lumbar Anulus Fibrosus. (PhD), The University of Adelaide. Abstract

Smith, L. J., Byers, S., Costi, J. J., & Fazzalari, N. L. (2008). Elastic fibers enhance the mechanical integrity of the human lumbar anulus fibrosus in the radial direction. Annals of biomedical engineering, 36(2), 214-223. Abstract

Cho, H., Park, K., Shim, J., Elder, S., Huang, J., Min, B., Robertson, J.T., Hasty, K. (2007). Construction of a tissue-engineered annulus fibrosus. Paper presented at the Transactions of the 53rd Annual Meeting of the Orthopaedic Research Society, San Diego, CA, USA.

Smith, L. J., Byers, S., Costi, J. J., & Fazzalari, N. L. (2007). The Roles of Elastic Fibres and Glycosaminoglycans in the Radial Tensile Mechanics of the Human Lumbar Anulus Fibrosus. Paper presented at the ASME 2007 Summer Bioengineering Conference. Abstract

Tissue Engineering - Articular Cartilage

Brenner, J. M., Kunz, M., Tse, M. Y., Winterborn, A., Bardana, D. D., Pang, S. C., & Waldman, S. D. (2013). Development of large engineered cartilage constructs from a small population of cells. Biotechnology progress, 29(1), 213-221. Abstract

Mintz, B. R., & Cooper, J. A. (2013). Hybrid hyaluronic acid hydrogel/poly (ɛ-caprolactone) scaffold provides mechanically favorable platform for cartilage tissue engineering studies. Journal of Biomedical Materials Research Part A Abstract

Petrera, M., Croos, D., Amritha, J., Iu, J., Hurtig, M., Kandel, R. A., & Theodoropoulos, J. S. (2013). Supplementation With Platelet-Rich Plasma Improves the In Vitro Formation of Tissue-Engineered Cartilage With Enhanced Mechanical Properties. Arthroscopy: The Journal of Arthroscopic & Related Surgery, 29(10), 1685-1692. Abstract

Brenner, J. (2012). Development and Validation of Large-Sized Engineering Cartilage Constructs in Full-Thickness Chondral Defects in a Rabbit Model. (Master), Queen's University. Abstract

Kaupp, J. A. (2012). Simulated Joint Loading Enhances the Expression of Superficial Zone Markers in Tissue Engineered Cartilage Constructs. (PhD), Queen's University. Abstract

Keeley, F., Rothstein, S., Rothstein, A., & Woodhouse, K. (2012). Synthetic peptide materials for joint reconstruction, repair and cushioning. Google Patents. Full Text

Khan, A. A. (2012). Effects of Additional Sodium Bicarbonate on Extra/intra Cellular Factors in a Continuous Flow Bioreactor for the Production of Tissue Engineered Articular Cartilage. (PhD), Queen's University. Abstract

Khan, A. A., & Surrao, D. C. (2011). The importance of bicarbonate and nonbicarbonate buffer systems in batch and continuous flow bioreactors for articular cartilage tissue engineering. Tissue Engineering Part C: Methods, 18(5), 358-368. Abstract

Lee, W. D., Hurtig, M. B., Kandel, R. A., & Stanford, W. L. (2011). Membrane culture of bone marrow stromal cells yields better tissue than pellet culture for engineering cartilage-bone substitute biphasic constructs in a two-step process. Tissue Engineering Part C: Methods, 17(9), 939-948. Abstract

Tran, S. C., Cooley, A. J., & Elder, S. H. (2011). Effect of a mechanical stimulation bioreactor on tissue engineered, scaffold-free cartilage. Biotechnology and bioengineering, 108(6), 1421-1429. Abstract

Croos, D., Amrith, J., Roughley, P. J., & Kandel, R. A. (2010). Improved bioengineered cartilage tissue formation following cyclic compression is dependent on upregulation of MT1-MMP. Journal of orthopaedic research, 28(7), 921-927. Abstract

Fan, J. C., & Waldman, S. D. (2010). The effect of intermittent static biaxial tensile strains on tissue engineered cartilage. Annals of biomedical engineering, 38(4), 1672-1682. Abstract

Hao, T., Wen, N., Cao, J.-K., Wang, H.-B., Lü, S.-H., Liu, T., Lin, Q-X., Duan, C-M.,Wang, C.-Y. (2010). The support of matrix accumulation and the promotion of sheep articular cartilage defects repair in vivo by chitosan hydrogels. Osteoarthritis and Cartilage, 18(2), 257-265. Abstract

Raizman, I., Croos, D., Amritha, J., Pilliar, R., & Kandel, R. A. (2010). Calcium regulates cyclic compression-induced early changes in chondrocytes during in vitro cartilage tissue formation. Cell calcium, 48(4), 232-242. Abstract

Spiteri, C., Raizman, I., Pilliar, R. M., & Kandel, R. A. (2010). Matrix accumulation by articular chondrocytes during mechanical stimulation is influenced by integrin-mediated cell spreading. Journal of Biomedical Materials Research Part A, 94(1), 122-129. Abstract

Usprech, J. (2010). A Therapeutic Dose of Adenosine Triphosphate (ATP) for Cartilage Tissue Engineering. (Master), Queen's University. Abstract

Waldman, S., Usprech, J., Flynn, L., & Khan, A. (2010). Harnessing the purinergic receptor pathway to develop functional engineered cartilage constructs. Osteoarthritis and Cartilage, 18(6), 864-872. Abstract

Dare, E. V., Griffith, M., Poitras, P., Kaupp, J. A., Waldman, S. D., Carlsson, D. J., Dervin, G., Mayoux, C., Hincke, M. T. (2009). Genipin cross-linked fibrin hydrogels for in vitro human articular cartilage tissue-engineered regeneration. Cells Tissues Organs, 190(6), 313-325. Abstract

De Croos, J., Pilliar, R., & Kandel, R. (2008). AP-1 DNA binding activity regulates the cartilage tissue remodeling process following cyclic compression in vitro. Biorheology, 45(3), 459-469. Abstract

De Croos, J., Jang, B., Dhaliwal, S., Grynpas, M., Pilliar, R., & Kandel, R. (2007). Membrane type-1 matrix metalloproteinase is induced following cyclic compression of in vitro grown bovine chondrocytes. Osteoarthritis and Cartilage, 15(11), 1301-1310. Abstract

Waldman, S. D., Couto, D. C., Grynpas, M. D., Pilliar, R. M., & Kandel, R. A. (2007). Multi-axial mechanical stimulation of tissue engineered cartilage: review. Eur Cell Mater, 13(613), 73-74. Abstract

Waldman, S., Couto, D., Grynpas, M., Pilliar, R., & Kandel, R. (2006). A single application of cyclic loading can accelerate matrix deposition and enhance the properties of tissue-engineered cartilage. Osteoarthritis and Cartilage, 14(4), 323-330. Abstract

De Croos, J., Dhaliwal, S., Grynpas, M., Pilliar, R., & Kandel, R. (2006). Cyclic compressive mechanical stimulation induces sequential catabolic and anabolic gene changes in chondrocytes resulting in increased extracellular matrix accumulation. Matrix Biology, 25(6), 323-331. Abstract

Hoemann, C., Sun, J., Legare, A., McKee, M., & Buschmann, M. (2005). Tissue engineering of cartilage using an injectable and adhesive chitosan-based cell-delivery vehicle. Osteoarthritis and Cartilage, 13(4), 318-329. Abstract

Tran-Khanh, N., Hoemann, C. D., McKee, M. D., Henderson, J. E., & Buschmann, M. D. (2005). Aged bovine chondrocytes display a diminished capacity to produce a collagen-rich, mechanically functional cartilage extracellular matrix. Journal of orthopaedic research, 23(6), 1354-1362. Poster, Abstract

Williams, G., Klein, T., & Sah, R. (2005). Cell density alters matrix accumulation in two distinct fractions and the mechanical integrity of alginate-chondrocyte constructs. Acta Biomater, 1(6), 625-633. Abstract

Waldman, S. D., Spiteri, C. G., Grynpas, M. D., Pilliar, R. M., & Kandel, R. A. (2004). Long-term intermittent compressive stimulation improves the composition and mechanical properties of tissue-engineered cartilage. Tissue engineering, 10(9-10), 1323-1331. Abstract

Waldman, S., Spiteri, C., Grynpas, M., Pilliar, R., & Kandel, R. (2003). Long-term intermittent shear deformation improves the quality of cartilaginous tissue formed in vitro. Journal of orthopaedic research, 21(4), 590-596. Abstract

Waldman, S. D., Grynpas, M. D., Pilliar, R. M., & Kandel, R. A. (2003). The use of specific chondrocyte populations to modulate the properties of tissue-engineered cartilage. Journal of orthopaedic research, 21(1), 132-138. Abstract

Waldman, S. D., Spiteri, C. G., Grynpas, M. D., Pilliar, R. M., Hong, J., & Kandel, R. A. (2003). Effect of biomechanical conditioning on cartilaginous tissue formation in vitro. The Journal of Bone & Joint Surgery, 85(suppl_2), 101-105. Abstract

Waldman, S. D., Grynpas, M. D., Pilliar, R. M., & Kandel, R. A. (2002). Characterization of cartilagenous tissue formed on calcium polyphosphate substrates in vitro. Journal of biomedical materials research, 62(3), 323-330. Abstract

Tissue Engineering - Auricle Cartilage

Giardini-Rosa, R., Joazeiro, P. P., Thomas, K., Collavino, K., Weber, J., & Waldman, S. D. (2014). Development of scaffold-free elastic cartilaginous constructs with structural similarities to auricular cartilage. Tissue Engineering Part A. Abstract

Tissue Engineering - Bone

Hollenstein, J., Terrier, A., Cory, E., Chen, A. C., Sah, R. L., & Pioletti, D. P. (2013). Mechanical evaluation of a tissue-engineered zone of calcification in a bone-hydrogel osteochondral construct. Computer methods in biomechanics and biomedical engineering(ahead-of-print), 1-6. doi: 10.1080/10255842.2013.794898 Abstract

Jarry, C., Shive, M., & Chenite, A. (2007). An injectable biomaterial for bone repair. Materials science forum, 539-543, 535-539. doi: 10.4028/ Abstract

Tissue Engineering - Cardiac Tissue

Périé, D., Dahdah, N., Foudis, A., & Curnier, D. (2013). Multi-parametric MRI as an indirect evaluation tool of the mechanical properties of in-vitro cardiac tissues. BMC cardiovascular disorders, 13(1), 24-24. Abstract

Wang, B., Tedder, M. E., Perez, C. E., Wang, G., de Jongh Curry, A. L., To, F., Elder, S.H., Williams, L.N., Simionescu, D.T., Liao, J. (2012). Structural and biomechanical characterizations of porcine myocardial extracellular matrix. Journal of Materials Science: Materials in Medicine, 23(8), 1835-1847. Abstract

Tedder, M. E. B. (2010). Characterization and Evaluation of a Novel Tissue Engineered Aortic Heart Valve Construct. (PhD), Graduate School of Clemson University. Abstract

Wang, B., Borazjani, A., Tahai, M., de Jongh Curry, A. L., Simionescu, D. T., Guan, J., To, F., Elder, S.H., Liao, J. (2010). Fabrication of cardiac patch with decellularized porcine myocardial scaffold and bone marrow mononuclear cells. Journal of Biomedical Materials Research Part A, 94(4), 1100-1110. Abstract

Yip, C. Y. Y. (2010). Pathology of Calcific Aortic Valve Disease: The Role of Mechanical and Biochemical Stimuli in Modulating the Phenotype of and Calcification by Valvular Interstitial Cells. (PhD), University of Toronto. Full text

Yip, C., Chen, J., Zhao, R., & Simmons, C. (2009). Calcification by valve interstitial cells is regulated by the stiffness of the extracellular matrix. Arterioscler Thromb Vasc Biol, 29(6), 936-942. Abstract

Plantenga, T. L. (2007). Design of a fixture and method for direct measurement of the shear modulus of thin, soft polyacrylamide substrates. Abstract

Liu, Z., Iliopoulos, J., Gillies, R., O'Rourke, M., Avolio, A., & Walsh, W. (2001). BM10: Cyclic Preconditioning of Sheep Aorta. Australasian Physical & Engineering Sciences in Medicine, 24(4), 271. Abstract

Tissue Engineering - Central Nervous System

Leipzig, N. D., & Shoichet, M. S. (2009). The effect of substrate stiffness on adult neural stem cell behavior. Biomaterials, 30(36), 6867-6878. Abstract

Leipzig, N., & Shoichet, M. (2008). Neural stem cell 2D and 3D responses to substrate stiffness. Paper presented at the Biomedical Engineering Society Annual Fall Meeting, St. Louis, MO, USA.

Leipzig, N., & Shoichet, M. (2008). Photopolymerizable chitosan for studying the effects of substrate stiffness on neural stem cell differentiation. Paper presented at the World Biomaterials Congress 2008, Amsterdam, The Netherlands.

Leipzig, N., & Shoichet, M. (2007). Neural progenitor cell differentiation and the effects of substrate stiffness. Paper presented at the Stem Cell Network Annual General Meeting, Toronto, ON, Canada.

Tissue Engineering - Ligaments

Chen, F., Hayami, J. W., & Amsden, B. G. (2014). Electrospun Poly (L-lactide-co-acryloyl carbonate) Fibre Scaffolds With a Mechanically Stable Crimp Structure For Ligament Tissue Engineering. Biomacromolecules. Abstract

Surrao, D. (2012). Biomimetic scaffolds for ligament tissue engineering. (PhD), Queen's University. Abstract

Surrao, D. C., Fan, J. C., Waldman, S. D., & Amsden, B. G. (2012). A crimp-like microarchitecture improves tissue production in fibrous ligament scaffolds in response to mechanical stimuli. Acta biomaterialia, 8(10), 3704-3713. Abstract

Surrao, D. C., Waldman, S. D., & Amsden, B. G. (2012). Biomimetic poly (lactide) based fibrous scaffolds for ligament tissue engineering. Acta biomaterialia, 8(11), 3997-4006. Abstract

Hayami, J. W., Surrao, D. C., Waldman, S. D., & Amsden, B. G. (2010). Design and characterization of a biodegradable composite scaffold for ligament tissue engineering. Journal of Biomedical Materials Research Part A, 92(4), 1407-1420. Abstract

Wu, X., & Wang, X. (2010). Advanced bioreactor for ligament tissue engineering. Paper presented at the Mechatronics and Automation (ICMA), 2010 International Conference on. Abstract

Tissue Engineering - Nucleus Pulposus

Kandel, R. (2012). Intervertebral disc, Google Patents. Full text

Hamilton, D. J., Pilliar, R. M., Waldman, S., & Kandel, R. A. (2010). Effect of circumferential constraint on nucleus pulposus tissue in vitro. The Spine Journal, 10(2), 174-183. Abstract

Khan, O. F., Jean-Francois, J., & Sefton, M. V. (2010). MMP levels in the response to degradable implants in the presence of a hydroxamate-based matrix metalloproteinase sequestering biomaterial in vivo. Journal of Biomedical Materials Research Part A, 93(4), 1368-1379. Abstract

Séguin, C. A., Grynpas, M. D., Pilliar, R. M., Waldman, S. D., & Kandel, R. A. (2004). Tissue engineered nucleus pulposus tissue formed on a porous calcium polyphosphate substrate. Spine, 29(12), 1299-1306. Abstract